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KMID : 0043319880110010061
Archives of Pharmacal Research
1988 Volume.11 No. 1 p.61 ~ p.64
Studies on the Antibiotic Constituents of Korean Basidiomycetes(IV). Preliminary examination of the mycelial cultures of the 17 basidiomycetous strains
Chung KS
Chung SH/Kim BK
Abstract
To investigate the antibiotic constituents of Korean basidiomycetes the carpophores of the wood-rotting basidiomycetes were collected from several locations of Korea, and from them 17 mycelial strains were isolated on potato-dextrose-agar plates supplemented with tetracycline (20g/ml). The isolated strains were shake-cultured in glucose-peptone-yeast extract medium and then the antibacterial activities of the culture filtrates were assessed by disc-plate method. Among them, 12 strains (70.6%) were active, and basidiomycete strain LMCB-109 (Daedalea quercina) and LMCB-116 showed potent activities against all the six bacterial target organisms including Serratia marcescens.
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